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Ozone / oxygen therapy

The Ozone 2000 is the machine we use at the kurimed clinic The use of ozone in medicine was first extensively described by the Berlin doctor, Dr. Wolff during World War I, where remarkably good healing results were achieved in the therapy of gas ingestion and gas burns. Modern ozone therapy has been well researched in terms of its effects and limitations. It can be used by appropriately trained therapists in a variety of applications.

What is ozone and how does it help?

Usually, ozone is a colourless gas with a characteristic odour. It arises, for example, through ultraviolet radiation and provides the well-known ozone layer in the Earth's atmosphere endangered by environmental influences. Without this ozone layer, life on Earth would not be possible. Ozone can also kill viruses, bacteria and fungi. These properties of ozone have long been used e.g., for drinking water therapy and for the sterilization of swimming pools. Ozone therapy is not new but it is becoming increasingly important today, but even in the First World War, the Berlin doctor Wolff observed that festering wounds, gas gangrene and war injuries exhibited remarkably good healing characteristics when exposed to ozone. The ozone used today for medicinal purposes is made from pure oxygen. This ozone-oxygen mixture is tissue-friendly and causes a crucial improvement in circulation, so it seems obvious to use ozone as a therapeutic agent for the vascular diseases that accompany circulatory disorders.

From research on ozone therapy in different clinics the most important effects of ozone can be summarized:

1. The surface charge of the red blood cells is changed by ozone therapy so that coagulation can be prevented and reversed.

This prevents the so-called money roll formation, in which the blood corpuscles stick together and thus can no longer "pass through" the smallest vessels (capillaries) in sufficient number. If the capillaries supplying the blood no longer carry sufficient red blood cells, there is an undersupply of the affected areas. Depending on the affected area of the body, an organ disease, intermittent claudication, poor circulation in the legs, etc. can arise. Progression is usually slow and creeping, the consequences up to necessity of amputation, however, can be serious.

1.2 The surface of the red blood cells is loosened up.

This makes the red blood cells more elastic and easier to shape. This allows them to "fit" better in the narrow capillaries. In addition, elasticity of the red blood cells results in more effective release of oxygen from the blood to the environment in the capillaries: an elastic red blood cell flows through the capillaries in a rolling motion, not as a rigid sphere. The rolling motion brings much more surface of the blood cell into contact with the capillary surface. This, in turn, replicates an exchange surface for oxygen as opposed to simply "rolling" a rigid blood cell through a blood vessel. The more elastic the surface of the red blood cells is, the more oxygen enters our body.

1.3 Ozone has an antiseptic effect

Ozone kills viruses, fungi and bacteria very quickly. For this reason, ozone is also used instead of chlorine in drinking water therapy and swimming pool disinfection. This effect is used especially in the therapy of poorly healing wounds such as leg ulcers, decubital ulcers, fistulas, etc. Here ozone can be applied externally for longer periods of time.

1.4 Ozone reacts preferably with unsaturated fatty acids, it has a selective reactivity.

The products of this reaction can be detected as catalysts (i.e., substances that accelerate reactions) in the body. This property is based on the fact that in ozone therapy excretory substances such as uric acid, urea, creatinine and problematic blood components such as types of cholesterol and neutral fats are more effectively degraded in many cases. This can be demonstrated in simple blood tests. This invaluable effect has given the so-called "large autologous blood therapy with ozone" the popular name of "blood cleansing".

To sum up, the effects of ozone therapy described above thus help to improve or restore the nutrition and respiration of each individual cell. According to renowned scientists, these disorders are important factors in the development of many diseases, including cancer. This is why ozone therapy is used in many cancers, especially during radiation and chemotherapy.

The effects described above make ozone therapy a therapeutic factor in many diseases. However, it cannot be regarded as a panacea, but can be understood as a versatile, cause-centred therapeutic method.

2. What does ozone therapy look like?

2.1 Major autologous blood therapy

  1. In major autologous blood therapy, blood is withdrawn from the arm vein into a disposable dropper bottle.
  2. This blood is enriched with an ozone-oxygen mixture.
  3. The blood thus treated is then returned as an infusion via the existing venous access.

The amount of blood taken and the ozone-oxygen mixture added can vary, depending on the complaint / disease.

2.2 Minor autologous blood therapy

In the small autologous blood treatment, some venous blood is taken from the patient, shaken with an ozone-oxygen mixture and injected back into the gluteal muscle. Only sterile disposable syringes and cannulas are used for this purpose

2.3 Rectal fumigation with ozone

In rectal fumigation with ozone, a disposable catheter is introduced about 5-10 cm deep into the patient’s intestine. Then about 50ml-200 ml of ozone-oxygen mixture is slowly injected into the rectum with an enema syringe.

Patients who have been treated this way usually report that they were astonished how comparably simple this form of ozone-oxygen therapy is. The effect of a rectal ozone fumigation is comparable to that of a major autologous blood therapy.

If you are interested in an ozone-oxygen therapy, please contact us. Due to the administrative and legislative situation in Germany, we currently do not offer all possible variations of ozone-oxygen therapy.

3. Which method is the right one for me?

Which method is more suitable for the particular patient can only be clarified after a thorough examination by an experienced and well-trained ozone therapist. A well-trained therapist can be recognized by the certificate "Blue Card" HPGO3, which is only issued to ozone therapists certified by the Therapist Society for Ozone Therapy.

4. What risks are there?

Ozone therapy is a relatively safe procedure which, if properly carried out, would hardly lead to complications due to ozone administration. Nevertheless, every procedure and every therapy involves certain risks. There are certain medications that experience shows can not be combined well with ozone, there is a risk of syringe abscess as with any invasive surgery etc. We will be happy to clarify these in detail with you.

4.1 Ozone therapy should not be performed for the following conditions:

  1. Diseases of the heart that generally prohibit infusion treatment:
    1. WPW syndrome (a rare disorder of the transmission of stimuli from the atria to the ventricles with a tendency to dangerous arrhythmias),
    2.  Condition after a significant pulmonary embolism (with corresponding change in the right atrium)
    3.  Bifascicular block (a significant disturbance of the cardiac conduction system)
  2. Favism (an extremely rare congenital hereditary disease occurring in southern Mediterranean countries),
  3. Significant hyperthyroidism,
  4. Haemophiliacs (congenital disorders of the blood coagulation system).


4.2 Risks of ozone therapy

Fortunately, ozone therapy is a safe procedure which, if properly carried out, would not lead to any complication due to ozone administration. Nevertheless, a clarification must be made that takes into account the risks of the therapy process. For example, in the case of autologous blood therapy, a certain amount of pain can be expected during reinjection, which the patient must be able to tolerate. The same applies of course to the fumigation of wounds and subcutaneous injection (= injection under the skin) of ozone-oxygen gas mixture. A syringe abscess is not expected due to the microcidal properties of ozone, but still possible even with correct autologous blood injection. According to a court decision, the occurrence of a syringe abscess is still not proof of an error in therapy (OLG Cologne AZ: U 144/97). In this judgment, which was not pronounced in relation to ozone therapy, it is stated that: "Ultimately, abscesses cannot always be avoided even when all possible care is taken".

Unfortunately, there have been incidents with ozone therapy in the past, which were compiled and evaluated in a paper by Ms. Maria Therese Jacobs in 1980. 2,815 ozone therapists were invited to contribute, of whom 644 supported the investigation. A total of 384,775 patients were treated with ozone therapy in just under 5.6 million therapies. More than 90% of the therapists said that their success with ozone therapy was "very good" or "good". Only one therapist admitted to applying ozone therapy with poor success.

During these just under 5.6 million applications, 336 "incidents" were observed and further investigated. Even at the first analysis, it was found that in most of the minor undesirable effects in 309 cases ozone was not the trigger. Further research left 27 "incidents" that were attributable to the ozone. These were explained as follows:

a) What were the complications?

Two cases could be elucidated as hypoglycaemic conditions (= too low blood sugar level). Three were eczematous skin reactions. 11 Incidents were allergic reactions during ozone therapy. 11 could not be further clarified.

b) In what kind of ozone treatment did the complications occur?

15 of these complications occurred in the now obsolete intravenous gas injection, two in the now no longer common intra-arterial gas injection, seven in major autologous blood therapy and three occurred in the bag gas-exposure. Only 20% of ozone therapists involved in these cases stated that they have completed training in the form of a seminar. Considering these circumstances, even with techniques no longer used today (intra-arterial / venous gas injection) and therefore complications that won't occur today, the incidence rate has been miniscule at 0.000005 / ozone application. Today, an even lower probability of complications can be assumed with the possibilities of "latex-free ozone therapy", the different possibilities with regard to anticoagulation, and the requirement for training and further education of the therapists.

5. Which medications are incompatible?

Prior to ozone therapy, it goes without saying that in addition to an individual examination of the patients, an anamnesis (patient survey on previous illnesses, medication, allergies, etc.) should be carried out, taking into account all medicines that currently taken by the patient. The intake of drugs that prevent blood clotting (e.g. Macumar) prohibits, for example, injection into the muscles. However, a venipuncture can be performed, such as that in the above mentioned "blood cleansing". The therapist decides whether ozone therapy would be reasonable in this case, or is not likely to help in a given case. So far an undesirable interaction with ozone therapy has only been observed in the so-called "ACE inhibitors", for reducing blood pressure. When taking a medicine like this with a "1st generation” active ingredient, another blood pressure lowering medication should be used before the start of ozone therapy. Meanwhile, a variety of equally effective medicines with fewer side-effects is on the market, so that a conversion is easily possible. In any case, this must be agreed and carried out in advance with the attending physician.